Valid

GB/T 35823-2018Laboratory animals－General requirements for animal experiment (English PDF)

实验动物动物实验通用要求

Preview PDF

This is a limited preview

Buy now to download the full PDF (15 pages)

Need quotation for your management?

Get a formal quotation for GB/T 35823-2018 in 30 minutes.

Issued by

SAMR; SAC

Level / Type

National · Recommended

Issue date

February 6, 2018

Implementation date

September 1, 2018

Scope

GB/T 35823-2018 is the English-translated version of 实验动物动物实验通用要求.

GB/T 35823-2018 sets the general requirements that apply to animal experiments carried out by any institution in China.

It covers the review of experiments by the Institutional Animal Care and Use Committee, with its principles and procedure and the annual review of approved projects, the management of the animal laboratory, the experimental conditions, the quality of the laboratory animals and the basic technical operations.

These include restraint with fixation devices, anaesthesia and analgesia, postoperative care, humane endpoints, euthanasia and the treatment of carcasses and other waste.

It closes with experimental records and file management, and refers to the national standards on laboratory animal quality, feed, housing, biosafety and radiation protection.

Research institutes, universities and companies that use laboratory animals apply it. It was issued on 6 February 2018 and has applied since 1 September 2018.

Found what you need?

Document preview — GB/T 35823-2018

National Standard of the People's Republic of China

ICS: 65.020.30
Classification: B 44

Issued by: State Administration for Market Regulation; Standardization Administration of the PRC

Foreword3
1 Scope4
2 Normative references4
3 Terms and definitions5
4 Animal experiment review6
5 Animal laboratory management6
6 Experimental conditions7
7 Laboratory animal quality9
8 Basic technical operation specification9
9 Experimental record and file management11

1 Scope

This Standard specifies animal experiment review, laboratory management, experimental conditions, quality of laboratory animals, basic technical operations, experimental records and archiving requirements in various animal experiments.

This Standard is applicable to various institutions engaged in animal experiment.

2 Normative references

The following referenced documents are indispensable for the application of this document. For dated references, only the edition cited applies. For undated references, the latest edition of the referenced document (including any amendments) applies.

GB 5749, Standards for drinking water quality

GB 14922.1, Laboratory animal - Standards and monitoring for parasitology

GB 14922.2, Laboratory animal - Microbiological standards and monitoring

GB 14923, Laboratory animal - Genetic quality control of mammalian laboratory animals

GB/T 14924.1, Laboratory animals - General quality STANDARD for formula feeds

GB 14924.3, Laboratory animals - Nutrients for formula feeds

GB 14925, Laboratory animal - Requirements of environment and housing facilities

GB 18871, Basic Standards for Protection against Ionizing Radiation and for the Safety of Radiation Sources

GB 19489, Laboratories - General Requirements for Biosafety

GB/T 29510, General requirements for the distribution of personal protection

3 Terms and definitions

3.9 Humane endpoint

during the animal experiment, when the experimental results are known, the early stage of selecting the animal to express pain and pain is the end point of the experiment

3.10 Euthanasia

a method of humane termination of animal life that minimizes or eliminates animal panic and pain, allowing animals to die quietly and quickly

4 Animal experiment review

4.1 Responsibilities of Institutional Animal Care and Use Committee

The legal entity engaged in animal experiment work shall establish an experimental animal management committee, formulate the charter, review procedures, supervision system, regular meeting system, reporting system, work discipline, professional training plan, etc. of the experimental animal management committee.

4.2 Review principle

The review shall adhere to and abide by the principles of legitimacy, necessity, science, animal welfare, ethics, impartiality, balance of interests, etc.

4.3 Review procedure

4.3.1 The person in charge of various animal experiment projects shall submit an application for review to the experimental animal management committee, and the experimental animal management committee shall make an examination opinion.

4.3.2 The Institutional Animal Care and Use Committee shall implement an annual review of approved projects. Project leader submits project implementation. Modifications related to animal operations are subject to review by the Institutional Animal Care and Use Committee.

5 Animal laboratory management

5.1 Management agency

The animal experiment institution shall set up an animal experiment […]

8 Basic technical operation specification

8.4.2 Fixation devices shall be matched to the size of the animal, easy to operate, and can best meet animal welfare requirements. Before using fixation device, the adaptability training shall be performed for the animal.

8.4.3 Under the premise of meeting the experimental requirements, the fixation time shall be shortened as much as possible. When an animal has an abnormal condition during fixation, it shall be released from the fixation device as soon as possible.

8.5 Animal anesthesia and analgesia

8.5.1 Establish scientific and rational anesthesia and analgesia methods and related plans.

8.5.2 Personnel performing anesthesia shall undergo appropriate professional training and have the corresponding ability.

8.6 Postoperative care

Establish reasonable postoperative care, observation and related plans based on animal and surgical characteristics.

8.7 Humane endpoint

Develop and implement the humane endpoint table based on animal breeds and research purposes.

8.8 Euthanasia

8.8.1 Institutions conducting animal experiments shall comply with relevant regulations or guidelines. According to animal species, age, research purposes, safety and other factors, develop standard operating procedures for the implementation and evaluation of euthanasia.

8.8.2 The person responsible for implementing the euthanasia must undergo special training.

8.8.3 It is not advisable to have other animals present in the operation area where the euthanasia is implemented. The information of each animal must be confirmed before euthanasia. After the death is confirmed, it shall be treated harmlessly.

8.8.4 Non-human primates are not allowed to be executed in principle.

8.9 Waste treatment

Sewage, waste, animal carcasses, etc. produced by animal experiments shall be conducted in accordance with the requirements of GB 14925. […]

......
This preview omits tables, figures, formulas and parts of the technical clauses. The complete document — 15 pages — is available in the English PDF.

Referenced standards

Normative references

GB 14922.1 · GB 14922.2

Cited by

Similar standards

GB 47500-2026|GB 47738-2026|GB/T 14926.1-2026|GB/T 14926.19-2026|GB/T 14926.20-2026|GB/T 14926.22-2026

How to Download GB/T 35823-2018

1
Add to cart
Click "Download PDF" on this page and choose "Buy this standard". You can add more standards before checkout.
2
Checkout
Enter your email and billing details. Payment is processed securely by Stripe (cards or bank transfer). Prefer bank details? Request a quotation (min. order $300).
3
Instant delivery (0–9 sec)
Delivery is automatic: within seconds of payment you'll receive an email with a secure download link. The link stays valid for 72 hours.
4
Invoice included
A tax invoice is attached to the confirmation email. Need a custom invoice? Contact us.