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GB/T 47222-2026Technical specification for the biosafety control of animal experiments involving pathogenic infections (English PDF)

病原感染动物实验生物安全控制技术规范

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Issued by

SAMR; SAC

Level / Type

National · Recommended

Issue date

February 27, 2026

Implementation date

September 1, 2026

Scope

GB/T 47222-2026 is the English-translated version of 病原感染动物实验生物安全控制技术规范.

GB/T 47222-2026 is the Chinese standard "Technical specification for the biosafety control of animal experiments involving pathogenic infections".

Its scope clause reads: This document specifies the risk assessment, pre-experiment preparation, experiment implementation, emergency plans, records, and documentation procedures for animal experiments involving pathogen infection.

General requirements for biosafety control in case management. This document applies to biosafety control in animal experiments involving pathogen infection in animal biosafety laboratories. Its clauses include terms and definitions.

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Document preview — GB/T 47222-2026

National Standard of the People's Republic of China

ICS: 11.220
Classification: B 41

Issued by: State Administration for Market Regulation; Standardization Administration of the PRC

Preface
Introduction
1.Scope
2 Normative References
3.Terms and Definitions
4.Risk Assessment
5.Requirements for pre-experiment preparation activities
5.1 2 Experimenters
5.2 Facilities and Equipment
5.3 Laboratory Animals
6.Experimental Activity Requirements
6.1 Management and Transfer of Bacterial (Viral) Strains and Infectious Samples
6.2 Animal capture/restraint
6.3 Analgesia and Anesthesia
6.4 Inoculation and Administration
6.5 Sample Collection
6.6 The care of infected animals
6.7 Euthanasia
6.8 Autopsy and Sampling
6.9 Disinfection and Cleaning
6.10 Waste Disposal
7 Emergency Response Plan
8.Record and file management 7.

1 Scope

This document specifies the risk assessment, pre-experiment preparation, experiment implementation, emergency plans, records, and documentation procedures for animal experiments involving pathogen infection.

General requirements for biosafety control in case management.

This document applies to biosafety control in animal experiments involving pathogen infection in animal biosafety laboratories.

2 Normative references

The contents of the following documents, through normative references within the text, constitute essential provisions of this document. Dated citations are not included.

For references to documents, only the version corresponding to that date applies to this document; for undated references, the latest version (including all amendments) applies.

This document.

GB 8978 Integrated Wastewater Discharge Standard

GB 14925 Laboratory Animal Environment and Facilities

GB 15562.2 Environmental Protection Graphic Symbols for Solid Waste Storage (Disposal) Sites

GB/T 15981 Evaluation Method for Sterilization Efficacy of Disinfected Instruments

GB 18466 Standard for Water Pollutant Discharge from Medical Institutions

GB 18597 Standard for Pollution Control of Hazardous Waste Storage

GB 19489 General Requirements for Laboratory Biosafety

GB/T 39759 Terminology for Laboratory Animals

GB/T 39760 Guidelines for Euthanasia of Laboratory Animals

GB/T 43051 General Requirements for Biosafety in Laboratory Animals

GB 50346 Technical Specification for Biosafety Laboratory Construction

GB 50447 Technical Specifications for the Construction of Laboratory Animal Facilities

3 Terms and Definitions

The terms and definitions defined in GB/T 39759 and the following terms and definitions apply to this document.

3.1

Scientific research, teaching, testing, and other scientific experiments conducted using pathogen-infected laboratory animals or laboratory animals.

3.2 Terminal disinfection

After the experiment, a thorough disinfection is carried out to eliminate any pathogenic microorganisms that may remain in the experimental area.

3.3 laboratory waste

Substances generated during the experiment that have lost their value to the original user and are discarded or require disposal for reuse.

3.4 Infectious waste

Waste generated during animal experiments that contains or may contain pathogenic microorganisms and pose a risk of disease transmission to human or animal health.

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This preview omits tables, figures, formulas and parts of the technical clauses. The complete document — 10 pages — is available in the English PDF.

Referenced standards

Normative references

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