GB/T 42311-2023Nanotechnologies - Characterization of nanoparticles in inhalation exposure chambers for inhalation toxicity testing (English PDF)

1 Scope

This document provides the characterization of respirable nanoparticles in the respiratory exposure chamber for inhalation toxicity studies, including particle mass, size distribution, number concentration and composition:

2 Normative references

The contents of the following documents constitute the essential provisions of this document through normative references in the text: Among them, dated references

For documents, only the version corresponding to the date is applicable to this document; for undated reference documents, the latest version (including all amendments) is applicable to this document:

ISO 10312 Determination of asbestos fibers in ambient air Direct transfer transmission electron microscopy (Ambientair-Determina-

ISO /T S27687 Terms and definitions for nanotechnology nanoobjects Nanoparticles, nanofibers and nanosheets (Nanotechn-

Note: GB/T 32269-2015 Terms and definitions of nanotechnology nano-objects Nanoparticles, nanofibers and nanosheets (ISO /T S27687:2008,

IDT)

Note: GB/T 21605-2008 Test methods for acute inhalation toxicity of chemicals (OECD No:403:1981, OECD No:433:2002, MOD)

Note: GB/T 21754-2008 Chemical 28-day/14-day repeated dose inhalation toxicity test method (OECD No:412:2005, IDT)

Note: GB/T 21765-2008 Test method for subchronic inhalation toxicity of chemicals (OECD No:413:1981, IDT)

1) This guideline is published by the Organization for Economic Co-operation and Development (OECD):

3 Terms and Definitions

The following terms and definitions as defined in ISO 15900 and ISO /T S27687 apply to this document:

3:1 Particle measurement system

3:1:1

A classifier that can select the appropriate size of aerosol particles to enter and pass through the corresponding channel:

GBZ/T 300.61 | GBZ/T 300.68 | GBZ/T 276 | GB/T 33715 | GB/T 16124 | […]