GB/T 42241-2022Nanotechnology—Determination of [60]/[70] fullerene purity—High performance liquid chromatography (English PDF)

Foreword

This document is in accordance with the provisions of GB/T 1.1-2020 "Guidelines for Standardization Work Part 1: Structure and Drafting Rules for Standardization Documents" drafting.

Introduction

Fullerene is a closed cage molecule composed of carbon atoms, which is an allotrope of carbon, and its molecular size is less than 1nm. about. Due to their unique electronic conjugated structure, fullerenes have excellent optical, electrical and magnetic properties, so they are widely used in biomedicine, new materials and new energy.

Sources and other fields have a wide range of applications. The purity of fullerene is a key indicator affecting its application performance and market value. cosmetics and biomedicine There is a huge demand for high-purity fullerenes in the pharmaceutical industry. Therefore, formulating the standard for the detection method of fullerene purity can be a great contribution to fullerene scientific research institutes, Fullerene production enterprises and third-party testing institutions provide unified and standardized testing methods, which will promote the improvement of the quality of fullerene materials and related products. The rapid development of the industry is of great significance.

Determination of the Purity of [60]/[70] Fullerenes in Nanotechnology HPLC Caution. Personnel using this document should have practical experience in formal laboratory work. This document does not address all possible security issues.

Some of the test procedures specified in this document may lead to hazardous conditions. It is the user's responsibility to take appropriate safety and health measures and ensure that their Comply with the conditions stipulated by the relevant national laws and regulations.

1 Scope

This document describes a method for the determination of the purity of [60]/[70]fullerenes by HPLC.

This document is applicable to the determination of the purity of [60]/[70]fullerene, and the determination of the purity of other fullerenes and fullerene derivatives refers to this document implement.

2 Normative references

The contents of the following documents constitute the essential provisions of this document through normative references in the text. Among them, dated references For documents, only the version corresponding to the date is applicable to this document; for undated reference documents, the latest version (including all amendments) is applicable to this document.

GB/T 9008 Liquid Chromatography Terminology Column Chromatography and Planar Chromatography

GB/T 26792-2019 High Performance Liquid Chromatography

3 Terms and Definitions

The following terms and definitions defined in GB/T 9008 apply to this document.

4 Principles

The [60]/[70]fullerene sample was dissolved in toluene, the electronic conjugation effect of [60]/[70]fullerene and impurities in the sample solution and the molecular polarity The difference in property makes the chromatographic retention time different, detected by ultraviolet detector (or diode array detector), and calculated by peak area normalization method Purity of fullerene samples.