GB/T 33260.5-2018Capability of detection -- Part 5: Methodology in the linear and nonlinear calibration cases (English PDF)

1 Scope

This part of GB/T 33260 is mainly applicable to the case where the calibration function is non-linear and can also be used for linear cases.

The basic methods given in this section are used to.

--- Construct a precision profile function of the response variable, a function of the net state variable, using the standard deviation (SD) or variation of the response variable

Different coefficient (CV) representation;

--- Using the calibration function, the precision profile function of the response variable is transformed into the precision profile function of the net state variable;

--- Use the precision profile function of the net state variable to estimate the critical value and the minimum detectable value of the net state variable.

When the method given in GB/T 33260.2-2018 is not effective for the detection of various types of measurement methods (measurement equipment)

The methods presented in this section are very useful when evaluating. This includes measuring the loop by competitive ELISA (enzyme-linked immunosorbent assay)

Persistent organic pollutants (POPs, such as dioxin, pesticides and hormonal chemicals) and bacterial toxins that cause high fever.

GB/T 33260.1-2016 and GB/T 33260.2-2018 describe the threshold value of the net state variable and the minimum detectable value

Righteousness and applicability. This section extends the concept in GB/T 33260.2 to a non-linear calibration scenario.

Both the critical value xc and the minimum detectable value xd are given in units of net state variables. If xc and x are defined based on the distribution of response variables

Xd, then this definition should include a calibration function that transforms the response variable into a net state variable. The xc and xd defined in this section are based on the net shape

The distribution of state variables is independent of the form of the calibration function. Therefore, this definition applies regardless of whether the function form is linear or non-linear.

The calibration function should be continuous, divisible, and monotonically increasing or decreasing.

This section further gives a description of how SD or CV is known only in the neighborhood of the smallest detectable value.

Some examples are given in Chapter 6.

2 Normative references

The following referenced documents are indispensable for the application of this document. For dated references, only dated versions apply.

This document. For undated references, the latest edition (including all amendments) applies to this document.

GB/T 3358.1-2009 Statistical vocabulary and symbols - Part 1. General statistical terms and terms for probabilities (ISO 3534-1.2006, IDT)

GB/T 3358.2-2009 Statistical vocabulary and symbols - Part 2. Application statistics (ISO 3534-2.2006, IDT)

GB/T 3358.3-2009 Statistical vocabulary and symbols - Part 3. Experimental design (ISO 3534-3..1999, IDT)

GB/T 6379.1-2004 Accuracy of measurement methods and results (accuracy and precision) Part 1. General and definition (ISO 5725-1.1994, IDT)

GB/T 33260.1-2016 Detection capability Part 1. Terms and definitions (ISO 11843-1.1997, MOD)

GB/T 33260.2-2018 Detection capability Part 2. Methods for determining the ability to detect linear calibrations (ISO 11843-2.

2000, MOD)

3 Terms and definitions

GB/T 2829 | GB/T 6379.6 | GB/T 2828.2 | GB/T 33260.4 | GB/T 33260.3 | GB/T 33260.2 | […]