GB/T 29636-2023Examination methods for methamphetamine in suspected drugs (English PDF)

Foreword

This document complies with the provisions of GB/T 1.1-2020 "Standardization Work Guidelines Part 1: Structure and Drafting Rules of Standardization Documents" Drafting.

This document replaces GB/T 29636-2013 "Gas chromatography, high performance liquid chromatography and gas chromatography-mass spectrometry of methamphetamine in suspected drugs" "Spectral Inspection Method", compared with GB/T 29636-2013, in addition to structural adjustments and editorial changes, the main technical changes are as follows.

---Changed the "scope" (see Chapter 1, Chapter 1 of the 2013 edition);

---Added the principle of liquid chromatography-mass spectrometry method (see Chapter 4);

---Changed the reagents used in gas chromatography and gas chromatography-mass spectrometry (see 5.1.1, 2013 version of 5.1.1);

---Added reagents, instruments and materials for liquid chromatography-mass spectrometry analysis (see Chapter 5);

---Changed the sample preparation of gas chromatography-mass spectrometry and gas chromatography (see 6.1, 6.2, 6.1, 7.1, 7.2 of the 2013 version);

---Added liquid chromatography-mass spectrometry analysis method (see 7.1);

---Changed the liquid chromatography analysis method (see 7.2, 7.3 of the 2013 edition);

---Changed the "result evaluation" (see Chapter 8, Chapter 8 of the 2013 edition).

1 Scope

This document specifies the gas chromatography-mass spectrometry (GC-MS), liquid chromatography-mass spectrometry (LC-MS) qualitative testing methods and gas Principles, reagents, instruments and materials, inspection and analysis steps and result evaluation of chromatography (GC) and liquid chromatography (LC) quantitative testing methods.

This document is applicable to the qualitative and quantitative analysis of methamphetamine in suspected drugs.

2 Normative reference documents

The contents of the following documents constitute essential provisions of this document through normative references in the text. Among them, the dated quotations For undated referenced documents, only the version corresponding to that date applies to this document; for undated referenced documents, the latest version (including all amendments) applies to this document.

GB/T 6682 Specifications and test methods for water used in analytical laboratories

GB/T 27418 Evaluation and expression of measurement uncertainty

GA/T 122 Toxicological analysis terminology

3 Terms and definitions

The terms and definitions defined in GA/T 122 apply to this document.

4 Principles

Extraction of methamphetamine in suspected drugs. Gas chromatography-mass spectrometry was used for detection, with retention time, mass spectrum characteristic ions and The ion abundance ratio is used as the basis for qualitative judgment; liquid chromatography-mass spectrometry is used for detection, based on retention time, mass spectrum characteristic ion pair and ion pair abundance.

The ratio is used as the basis for qualitative judgment; gas chromatography is used for detection, and the chromatographic peak area (or peak area ratio) is used as the quantitative basis, and an external standard single point is used. method or internal standard standard curve method for quantitative analysis; liquid chromatography is used for detection, using the chromatographic peak area as the quantitative basis, and external standard single-point method Or external standard curve method for quantitative analysis.

5 Reagents, instruments and materials