GB/T 22985-2008Determination of enrofloxacin, danofloxacin, ciprofloxacin, sarafloxacin, orbifloxacin, difloxacin and marbofloxacin in milk and milk powder - LC-MS-MS method (English PDF)

1 Scope

This standard specifies the milk and milk powder enrofloxacin, danofloxacin, ciprofloxacin, sarafloxacin, Orbifloxacin, difloxacin and Ma Bao

Shaxing residues in liquid chromatography - tandem mass spectrometry.

This standard applies to milk and milk powder enrofloxacin, danofloxacin, ciprofloxacin, sarafloxacin, Orbifloxacin, difloxacin and Ma Bao

Determination of gatifloxacin residues and confirmation.

The standard method detection limit. milk enrofloxacin, danofloxacin, ciprofloxacin, sarafloxacin, Orbifloxacin, difloxacin and Ma Bao

Gatifloxacin were 1µg/kg; milk enrofloxacin, danofloxacin, ciprofloxacin, sarafloxacin, Orbifloxacin, difloxacin and marbofloxacin were

Of 4µg/kg.

2 Normative references

The following documents contain provisions which, through reference in this standard and become the standard terms. For dated references, subsequent

Amendments (not including errata content) or revisions do not apply to this standard, however, encourage the parties to the agreement are based on research

Whether the latest versions of these documents. For undated reference documents, the latest versions apply to this standard.

GB/T 6379.1 measurement methods and results of Accuracy (trueness and precision) - Part 1. General principles and definitions (GB/T 6379.1-2004, ISO 5725-1.1994, IDT)

GB/T 6379.2 measurement methods and results of Accuracy (trueness and precision) - Part 2. Determine the standard measurement method to repeat

Of the basic methods of reproduction (GB/T 6379.2-2004, ISO 5725-2.1994, IDT)

GB/T 6682 analytical laboratory use specifications and test methods (GB/T 6682-2008, ISO 3696. 1987, MOD)

Principle 3

Extracted with acetonitrile and phosphate buffer solution remaining in the sample enrofloxacin, danofloxacin, ciprofloxacin, sarafloxacin, Orbifloxacin,

Difloxacin and marbofloxacin, OasisHLB SPE column 1) purification, 5% methanol solution of aqueous ammonia, liquid chromatography - tandem mass spectrometry,

External standard.

1) OasisHLB solid phase extraction columns are Waters company's product trade name, this information is given for the convenience of users of this standard, not the table

Endorsement of the product shown. If other product has the same effect, you can use these equivalent products.

4 Reagents and materials

Unless otherwise stated, all reagents superior grade of pure water as a water GB/T 6682 regulations.