GB 28149-2011Chlorsulfuron wettable powders (English PDF)

3.1 Composition and appearance

This product should meet the criteria of the drug and chlorsulfuron appropriate processing auxiliaries and fillers are made as loose powder uniformly, there should be no lumps.

3.2 Technical Specifications

Chlorsulfuron WP should meet the requirements in Table 1.

Table 1 Control chlorsulfuron WP Item Index

project

index

10% 20% 25%

Chlorsulfuron mass fraction /% 10.0 20.0 1.2-1.2 25.0 1.5-1.5 1.0 to 1.0 Moisture content /% <= 2.5 pH range 6.0 to 9.0 TABLE 1 (cont.) project index 10% 20% 25% Wetting time/s <= 60 Fineness (44µm test sieve) /% >= 98 Suspension rate /% >= 85 Passing a heat storage stability test when a normal production, the thermal storage stability test was measured at least once every three months.

Test Method 4

Safety Tips. to use this standard shall have practical experience of laboratory work. This standard does not indicate any safety issues. Make with those who have the responsibility to take appropriate safety and health practices and to ensure compliance with the provisions of relevant state laws and regulations.

4.1 General provisions

This standard reagent in the absence of water and other requirements stated, refer to three predetermined analytical reagents and GB/T 6682-2008 of water. The test results performed by determining 4.3.3 rounding value in comparison 8170-2008 GB/T .

4.2 Sampling

Carried out in GB/T 1605-2001 of "commodity solid preparation sampling" approach. Determining Sample packages with a random number table method; final draw Sample size should be less than 300g.

4.3 Identification Test

The present liquid chromatography --- identification test can be carried out simultaneously with the determination of the mass fraction of chlorsulfuron. Chromatography under the same operating conditions, the test Comp retention time of the standard solution chlorsulfuron peak retention time of a peak solution, the relative difference of 1.5% should be or less.

4.4 Determination of the mass fraction of chlorsulfuron

4.4.1 Method summary

Sample solution was dissolved in methanol with aqueous ammonia, acetic acid in acetonitrile and water as mobile phase, using Nova-PakC18 filler to a stainless steel column and a UV detector (230nm), the sample chlorsulfuron and high performance liquid chromatography assay.

4.4.2 Reagents and solutions

Methanol. HPLC grade;

Acetonitrile. HPLC grade;

Glacial acetic acid;

Water. The new secondary steam distilled water;

Aqueous ammonia. w (NH3) = 26% ~ 30%;

Ammonia solution. [Psi] (ammonia. water) = 1.300;

Ammonia in methanol. [Psi] (ammonia solution. methanol) = 1.4;

Chlorsulfuron Sample. chlorsulfuron known mass fraction w>=98.0%.

4.4.3 Instruments

HPLC. a variable wavelength UV detector;

Chromatographic data processor;

Column. 150mm × 3.9mm (id) stainless steel column Nova-PakC18 filler contents (or equivalent effect column);

Filter. membrane pore size of about 0.45 m;

Microsyringe. 50µL;

Quantitative sampling tube. 5µL;

Ultrasonic cleaning.

4.4.4 HPLC operating conditions

Mobile phase. Psi (CH3CN.H2O.CH3COOH) = 40.60.0.5;

Flow rate. 1.0mL/min;

Column temperature. room temperature (temperature change should be less than 2 deg.] C);

Detection wavelength. 230nm;

Injection Volume. 5µL;

Retention time. chlorsulfuron about 4.3min.

Are typical operating parameters of the above, according to the characteristics of different instruments, for a given operating parameters appropriately adjusted to obtain the best result.

Typical wettable powders chlorsulfuron HPLC is shown in Figure 1.

1 --- chlorsulfuron.

HPLC chlorsulfuron FIG. 1 Wettable Powder

4.4.5 Determination Step

4.4.5.1 Preparation of standard solution

Weigh 0.05g chlorsulfuron standard (accurate to 0.0001g), a 100mL volumetric flask, dilute to volume with methanol solution of ammonia, to dissolve the sample ultrasonic vibration 5min, cooled to room temperature, shaking.

4.4.5.2 Preparation of sample solution

Weigh 0.05g of chlorine-containing specimens chlorsulfuron (accurate to 0.0001g), a 100mL volumetric flask, diluted with methanol solution of ammonia to Scale, to dissolve the sample ultrasonic vibration 5min, cooled to room temperature, shaken and filtered.

4.4.5.3 Determination

Under the above operating conditions, after the instrument is stable, the number of consecutive doses of the standard solution is injected until the two needles chlorsulfuron relative change in peak area adjacent After less than 1.2%, measured according to the standard solution, sample solution, the sample solution, the order of standard solution.

4.4.6 Computing

The mass fraction of the sample according to chlorsulfuron formula (1).

w1 = A2

· M1 · w

A1 · m2

Where.

W1 --- chlorsulfuron sample mass fraction in%;

A2 --- sample solution, the average peak area chlorsulfuron;

M1 --- Sample mass in grams (G);

W --- chlorsulfuron standard mass fraction in%;

A1 --- the standard solution, the average peak area chlorsulfuron;

--- M2 sample mass, in grams (g).

4.4.7 Allows poor

Results difference chlorsulfuron replicates should be less than twice the mass fraction of 0.5%, and the arithmetic mean value as a measurement result.

4.5 Determination of Moisture

According to GB/T 1600 in the "azeotropic distillation method".

4.6 PH value measured

Carried out in GB/T 1601.

4.7 Determination of the suspension rate

Proceed as GB/T 14825-2006 4.1. Weigh 0.2g of chlorine-containing specimens chlorsulfuron (accurate to 0.0001g), the bottom of the cylinder 25mL whole suspension was transferred to 100mL volumetric flask, with ammonia in methanol to volume, shaken at 3min ultrasound, static Set, after filtration, was measured according to 4.4 mass chlorsulfuron, calculate suspensibility.

4.8 Determination of wetting time

Carried out in GB/T 5451.

4.9 Determination of fineness

According to GB/T 16150 in the "wet sieve method".

4.10 Thermal storage stability test

According to GB/T 19136 in the "solid preparation" performed. After the heat storage mass chlorsulfuron fraction should be not less than 97% of the average content before storage, the suspension Rate should meet the standards for qualified.

4.11 Product inspection and acceptance

Shall comply with the provisions of GB/T 1604's.

5.1 Marking, labeling, packaging

Flag chlorsulfuron wettable powder, label, package should meet the requirements of GB 3796; chlorsulfuron aluminum bags Application WP or composite aluminum bag. The user may also request or order other forms of packaging protocols, subject to the provisions of GB 3796.

5.2 Storage

Chlorsulfuron WP package airiness, dry place; storage and transportation, prevent moisture and sunlight, no food, seed Promoter, feed-mixing, avoid contact with the skin, eyes, mouth and nose to prevent inhalation.

5.3 Security

This product is a low toxicity of sulfonylurea herbicides. Are swallowed and inhaled toxic, it can penetrate through the skin. When using this product to avoid contact with the skin, After application with soap and rinse with water. Poisoning should immediately sent to hospital for symptomatic treatment.

5.4 Warranty Period

Warranty. Under the provisions of storage and transportation conditions, chlorsulfuron WP warranty period of two years from the date of manufacture.

Appendix A

(Informative)

Other names chlorsulfuron, structural formulas and physicochemical parameters of the basic this product is an active ingredient chloro other names, structural formulas and physicochemical parameters of the basic metsulfuron follows.

ISO common name. Chlorsulfuron CAS Registry Number. 64902-72-3 CIPAC Numeric Code. 391 Chemical name. 1- (2-chlorophenyl) -3- (4-methoxy-6-methyl-1,3,5-triazin-2-yl) urea Structure.

Empirical formula. C12H12ClN5O4S Molecular weight. 357.8 Biological activity. weeding Melting point. about 174 °C ~ 178 °C Vapor pressure (25 °C). 3nPa Solubility (22 °C, g/L). 57 acetone; dichloromethane 102; 14 methanol; toluene 3; hexane 0.01; water 0.1 ~ 0.125 (25 °C, pH4.1), 0.3 (25 °C, pH5) Stability. when dry, light stability; in the soil, due to hydrolysis and microbial degradation and damage; half-life in soil 150d ~ 160d.