GB 28141-2011Imidacloprid soluble concentrate (English PDF)

3.1 Composition and appearance

This product shall be made compliant imidacloprid and necessary auxiliaries, should be stable homogeneous liquid, no visible suspended matter and precipitation.

3.2 Technical Specifications

Imidacloprid solution may be in accordance with Table 1.

Table 1 imidacloprid solution may be controlled Item Index

project

index

5% 10% 20%

Imidacloprid mass fraction /% 5.0 0.5-0.5 1.2-1.2 20.0 10.0 1.0 to 1.0 Moisture /% <= 0.5 the pH range of 5.0 to 8.0 TABLE 1 (cont.) project index 5% 10% 20% Qualified solution stability Low temperature stability of a qualified Passing a heat storage stability Low temperature stability test, the thermal storage stability test was measured every three months, at least once during a normal production.

Test Method 4

Safety Tips. to use this standard shall have practical experience of laboratory work. This standard does not indicate any safety issues. Make with those who have the responsibility to take appropriate safety and health practices and to ensure compliance with the provisions of relevant state laws and regulations.

4.1 General provisions

This standard reagent in the absence of water and other requirements stated, refer to three predetermined analytical reagents and GB/T 6682-2008 of water. The test results performed by determining 4.3.3 rounding value in comparison 8170-2008 GB/T .

4.2 Sampling

Carried out in GB/T 1605-2001 of "liquid formulation sampling" approach. Determining Sample packages with a random number table method; final sample size not less than 200mL.

4.3 Identification Test

The present liquid chromatography ---- identification test can be conducted simultaneously with the determination of the mass fraction of imidacloprid. Chromatography under the same operating conditions, A peak sample solution retention time in the standard solution imidacloprid retention time of the peaks, the relative difference of 1.5% should be or less.

4.4 Determination of the content of Imidacloprid

4.4.1 Method summary

Sample dissolved in mobile phase, methanol and water as mobile phase, used as a filler C18 stainless steel column and UV detector at a wavelength of at 260nm, of the sample imidacloprid RP-HPLC separation and determination, external standard.

4.4.2 Reagents and solutions

Methanol. HPLC grade;

Water. The new secondary steam distilled water;

Imidacloprid Sample. A known mass fraction w>=99.0%.

4.4.3 Instruments

HPLC. a variable wavelength UV detector;

Chromatographic data processor or chromatography workstation;

Column. 250mm × 4.6mm (id) stainless steel column, C18,5µm filler contents (or column with equivalent effect);

Filter. membrane pore size of about 0.45 m;

Microsyringe. 50µL;

Quantitative sampling tube. 5µL;

Ultrasonic cleaning.

4.4.4 HPLC operating conditions

Mobile phase. [Psi] (methanol. water) = 40.60, by membrane filtration, and degassing;

Flow rate. 0.8mL/min;

Column temperature. room temperature (temperature change should be less than 2 deg.] C);

Detection wavelength. 260nm;

Injection Volume. 5µL;

Retention time. imidacloprid about 6.0min.

Are typical operating parameters of the above, according to the characteristics of different instruments, for a given operating parameters appropriately adjusted to obtain the best result.

A typical solution may imidacloprid HPLC is shown in Figure 1.

1 --- imidacloprid.

HPLC FIG 1 FIG solutions can imidacloprid

4.4.5 Determination Step

4.4.5.1 Preparation of standard solution

0.1 g of weighed (accurate to 0.0002g) imidacloprid in Sample 100mL volumetric flask, diluted with methanol to the mark, the ultrasonic oscillation 5min to dissolve the sample, cooled to room temperature, shaking. Pipette with a pipette 5mL above solution in 50mL volumetric flask, dilute with the mobile phase Release to the mark.

4.4.5.2 Preparation of sample solution

Containing 0.1 g of imidacloprid was weighed (accurate to 0.0002g) sample in 100mL volumetric flask, diluted with methanol to the mark, the ultrasonic vibrator 5min swing dissolve the sample cooled to room temperature, shaking. Pipette with a pipette 5mL above solution in 50mL volumetric flask, with the mobile phase Diluted to the mark.

4.4.5.3 Determination

Under the above operating conditions, after the instrument is stable, the number of consecutive doses of the standard solution is injected until the two adjacent pins relative change in peak area imidacloprid After less than 1.2%, measured according to the standard solution, sample solution, the sample solution, the order of standard solution.

4.4.5.4 Computing

The two needle and the sample solution was measured before and after the two doses of the standard sample solution and peak areas were averaged imidacloprid. Imidacloprid sample Mass fraction by formula (1).

w1 = A2

· M1 · w

A1 · m2

Where.

W1 --- imidacloprid sample mass fraction in%;

A2 --- sample solution, imidacloprid average peak area;

M1 --- imidacloprid standard mass in grams (G);

W --- the mass fraction of imidacloprid standard sample, expressed in%;

A1 --- the standard solution, the average peak area imidacloprid;

--- M2 sample mass, in grams (g).

4.4.6 Allows poor

The difference between the results of two replicates imidacloprid content should not exceed 0.5%, and the arithmetic mean value as a measurement result.

4.5 Determination of Moisture

According to GB/T 1600 in the "Karl Fischer method".

4.6 PH value measured

Carried out in GB/T 1601.

4.7 Solution stability

4.7.1 Reagents and Equipment

Standard hard water. rho (Ca2 Mg2) = 342mg/L, pH = 6.0 ~ 7.0, according to GB/T 14825 formulated.

Cylinder. 100mL.

4.7.2 Test Procedure

0.5mL pipette with the sample, a 100mL graduated cylinder and diluted to the mark with standard hard water, mixing, into this cylinder 30 °C ± 2 °C water bath, allowed to stand IH, diluent uniform, no precipitate qualified.

4.8 Low temperature stability test

Press 19137 of "emulsions and a homogeneous liquid formulation" GB/T performed. Precipitates no more than 0.3mL qualified.

Thermal storage stability test 4.9 According to GB/T 19136 of "liquid formulation" performed. After the heat storage mass fraction of imidacloprid to be not less than 97% before storage.

4.10 Product inspection and acceptance

Shall comply with the provisions of GB/T 1604's.

5.1 Marking, labeling, packaging

Brown glass bottles or PET bottles can be packaged imidacloprid solution with an application within the plug and the outer cover, the net content is generally bottle 100g, 500g and the like; packaging box or corrugated plastic boxes, each box weighing no more than 10kg. The user may also request or order protocol, using other forms of Type of packaging, subject to the provisions of GB 3796.

5.2 Storage

Imidacloprid solution package can airiness, dry place. Storage and transportation, to prevent moisture and sunlight, no food, seed Promoter, feed-mixing, avoid contact with the skin, eyes, mouth and nose to prevent inhalation.

5.3 Security

This formulation is low toxicity. It can penetrate through the skin. When using this product to avoid contact with the skin, application after application with soap and rinse with water.

Poisoning should immediately sent to hospital for symptomatic treatment.

5.4 Warranty Period

Storage conditions under predetermined period to ensure that the solution may be imidacloprid, two years from the production date.

Appendix A

(Informative)

Other names imidacloprid, structural formulas and physicochemical parameters of the basic Other names, structural formulas and physicochemical parameters of the product basic active ingredient imidacloprid is as follows.

ISO common name. Imidacloprid CAS Registry Number. 138261-41-3 CIPAC Numeric Code. 582 Chemical name. 1- (6-chloro-3-pyridylmethyl) -N- nitromethylene-imidazol-2-yl-amine Structure.

Empirical formula. C9H10ClN5O2 Molecular weight. 255.7 Biological activity. insecticide Melting point. 144 °C Vapor pressure (20 °C). 4 × 10-7mPa Solubility (20 °C, g/L). 0.61 water, 0.68 of toluene, 55 dichloromethane, 1.2 isopropanol, n-hexane is less than 0.1 Stability follows. pH of 5 to 11 stable, hard to be hydrolyzed.