SN/T 4152-2015Chemicals--Test guidance on aquatic hazards to the difficult test substances (English PDF)

Foreword

This standard is drafted in accordance with the rules given in GB/T 1.1-2009.

The technical content of this standard is in line with A9.3.5 in Annex 9 of the Globally Harmonized System of Classification and Labeling of Chemicals (English version, Third Revision) Consistent content.

This standard has the following structure and editorial changes.

- the addition of the scope chapter;

--- Added an abbreviation chapter;

The dosage unit is changed to our legal dosage unit.

This standard is proposed and approved by the National Certification and Accreditation Administration Committee.

The drafting unit of this standard. Tianjin Entry - Exit Inspection and Quarantine Bureau of the People's Republic of China.

Introduction

Effective aquatic toxicity tests require that the test substance be water-soluble under the recommended test conditions and that its bioavailability exposure the degree can remain constant throughout the test. Some chemicals are difficult to test in the aquatic system, and this has helped to do this Guidance on the testing of substances (Ministry of Energy, 1996. Center for Ecotoxicology and Toxicology, European Chemicals, 1996; USEPA, 1996).

The Organization for Economic Co-operation and Development (OECD) is currently finalizing the guidance document on the aquatic toxicity test of refractory substances and mixtures (economic Organization for Development and Development, 2000). The latter document is about the type of material that is difficult to test, and to ensure that the test of these substances is effective Need to take a good source of information for the steps.

However, many of the existing test data may use tests that are not currently considered to be the best, but can still be used to Class of standard information. This data, while ultimately requiring experts to determine their effectiveness, still needs to provide special guidance on data interpretation.

These refractory substances may be poorly soluble, unstable, or rapidly reduced in processes such as light conversion, hydrolysis, oxidation or biodegradation solution. In conducting algae tests, colored materials may affect the test results by attenuating the light required for cell growth. Similarly, as Higher than the solubility of the cloud-like dispersion test material, may lead to false toxicity test results. Load the water column with the test substance can not be applied to particles or solids such as metals. Petroleum fractions also have loading problems, in the test L (E) C50 value, how to take appropriate the concentration should also have difficult to explain the problem. This standard describes the refractory substances and mixtures of aquatic toxicity tests in most substances Common characteristics.

Classification of Aquatic Toxicity of Chemical Difficult to Test Substances

1 Scope

This standard specifies the abbreviations in the aquatic toxicity test of chemicals, the factors that affect the aquatic toxicity test, and the difficulties in the aquatic toxicity test.

Classification of test substances.

This standard applies to chemicals in aquatic toxicity test difficult to test substances.

2 Abbreviations

The following abbreviations apply to this document.

EC50. The concentration of the effective substance that causes 50% of the maximum response.

LC50. Chemical concentration in 50% (half) of a group of animals in air or water.

L (E) C50. LC50 or EC50.

Factors affecting aquatic toxicity