GB/T 43641-2024Technical specification for identification of biological full sibling relationship (English PDF)

生物学全同胞关系鉴定技术规范

Open the GB/T 43641-2024 preview as PDF

Preview — first pages of GB/T 43641-2024 (full document: 15 pages)

This is a limited preview

Buy now to download the full PDF (15 pages)

Issued by

SAMR; SAC

Level / Type

National · Recommended

Issue date

March 15, 2024

Implementation date

July 1, 2024

Scope

GB/T 43641-2024 is the English-translated version of 生物学全同胞关系鉴定技术规范.

GB/T 43641-2024 is the Chinese national standard covering technical specification for identification of biological full sibling relationship. Issued on 15 March 2024, it has been in force since 1 July 2024.

Document preview — GB/T 43641-2024

National Standard of the People's Republic of China

ICS: 11
Classification: C 06

Issued by: State Administration for Market Regulation; Standardization Administration of the PRC

PrefaceI
1 Scope1
2 Normative references1
3 Terms and Definitions1
4 Abbreviations2
5 General Requirements2
6 Inspection Procedure2
6.1 Sampling2
6.2 DNA extraction and purification3
6.3 DNA quantitative analysis3
6.4 PCR amplification and typing3
7 Parameter calculation and threshold determination5
7.1 IBS calculation for a single autosomal STR locus5
7.2 Calculation of CIBS5
7.3 FSI calculation for a single autosomal STR locus5
7.4 Calculation of CFSI6
7.5 CIBS determination threshold and corresponding system performance6
7.6 CFSI determination threshold and corresponding system performance8
8 Expert opinion9
9 Identification documents9
Reference10

Foreword

This document is in accordance with the provisions of GB/T 1.1-2020 "Guidelines for standardization work Part 1: Structure and drafting rules for standardization documents" Drafting.

Please note that some of the contents of this document may involve patents. The issuing organization of this document does not assume the responsibility for identifying patents.

This document is proposed and coordinated by the Ministry of Justice of the People's Republic of China.

This document was drafted by: Institute of Forensic Science, Sun Yat-sen University, Fudan University, Sichuan University, Hebei Medical University, Beijing Municipal Public Security Bureau Bureau, and the Supreme People’s Procuratorate’s Procuratorial Technology Information Research Center.

The main drafters of this document are: Li Chengtao, Liu Xiling, Sun Hongyu, Zhang Suhua, Hou Yiping, Li Shujin, Liu Yacheng, Li Yuanyuan and He Xiaodan.

Technical specification for identification of biological full sibling relationships

1 Scope

This document specifies the general requirements, testing procedures, and parameters for the use of autosomal STR loci for biological full-sib relationship testing.

Requirements for calculations, expert opinions and expert documents.

This document is applicable to the identification of biological full sibling relationships and unrelated individuals between two individuals.

This document is not applicable to the determination of other relatedness (such as half-siblings or cousins, etc.).

2 Normative references

The contents of the following documents constitute the essential clauses of this document through normative references in this document.

For referenced documents without a date, only the version corresponding to that date applies to this document; for referenced documents without a date, the latest version (including all amendments) applies to This document.

GA/T 1162 Specification for the collection, storage and submission of forensic biological specimens GA/T 1163 Analysis and application of human DNA fluorescent marker STR typing results SF/T 0069 Forensic evidence identification laboratory management specification SF/T 0134 Technical specification for nucleic acid extraction from forensic biological samples

3 Terms and definitions

The following terms and definitions apply to this document.

3.1 FS

Multiple offspring individuals with the same biological father and mother.

3.2 The process of making a judgment

Through the detection of human genetic markers and analysis of genetic laws, it is possible to determine whether the two individuals in dispute are full siblings (3.1).

3.3

For each STR locus, the number of identical alleles between two disputed individuals.

Note. Two individuals may have the same allele at the same locus. This may be due to inheritance or the consistency of random matching.

When multiple independent autosomal genetic markers are used When the typing system tests two controversial individuals, the sum of the IBS at each genetic marker is called the cumulative consistency score (CIBS).

3.4 Full sibling relationship index; FSI

For each STR locus, the probability of the genotype occurring when the two disputed individuals are full siblings (3.1) The ratio of the probability of the genotypes appearing when the two controversial individuals are unrelated is calculated as shown in formula (1).

......
This preview omits tables, figures, formulas and parts of the technical clauses. The complete document — 15 pages — is available in the English PDF.

Editions of GB/T 43641

Edition	Title	Revision	Status
GB/T 43641-2024	Technical specification for identification of biological full sibling relationship	current edition	Current

This page sells the current edition, GB/T 43641-2024. Earlier editions are listed for reference only.

How to Buy GB/T 43641-2024

1Add to cart. Click the "Buy GB/T 43641-2024" button on this page. You can add more standards before checkout.
2Checkout. Enter your email and billing details. Payment is processed securely by Stripe (cards, Apple Pay, Google Pay supported).
3Instant delivery (0–9 sec). Delivery is automatic: within seconds of payment you'll receive an email with a secure download link. The link stays valid for 72 hours.
4Invoice included. A tax invoice is attached to the confirmation email. Need a custom invoice? Contact us.