GB 29386-2012Deltamethrin emulsifiable concentrates (English PDF)

3.1 Composition and appearance

This product shall be made deltamethrin standard original drug, a stable homogeneous liquid, no visible precipitate or suspension.

3.2 Technical Specifications

Deltamethrin EC should also meet the requirements of Table 1.

Table 1 deltamethrin EC Control Project Index

project

index

25g/L 50g/L

Deltamethrin mass fraction a /% Deltamethrin or mass concentration (20 °C) / (g/L) 2.8 0.3-0.3 253-3 5.0 0.5-0.5 505-5 Moisture content /% <= 1.0 TABLE 1 (cont.) project index 25g/L 50g/L the pH range of 4.0 to 7.0 Emulsion stability (200-fold dilution) Eligible Low temperature stability Qualified b B qualified thermal storage stability Mass fraction measurement results to arbitration when a dispute occurred when the quality.

B When normal production, low temperature stability test, the thermal storage stability test was measured at least once every three months.

Test Method 4

Safety Tips. to use this standard shall have practical experience of laboratory work. This standard does not indicate any safety issues. Make with those who have the responsibility to take appropriate safety and health practices and to ensure compliance with the provisions of relevant state laws and regulations.

4.1 General provisions

This standard reagent in the absence of water and other requirements stated, refer to three predetermined analytical reagents and GB/T 6682-2008 of water. The test results performed by determining 4.3.3 rounding value in comparison 8170-2008 GB/T .

4.2 Sampling

Carried out in GB/T 1605-2001 of "liquid formulation sampling" approach. Determined by sampling a random number table method packages, the amount of the final sample not less than 200mL.

4.3 Identification Test

HPLC --- This identification test can be carried out simultaneously with the determination of the content of deltamethrin. Chromatography under the same operating conditions, Deltamethrin peaks in the sample solution for a retention time of peaks and the retention time of the standard solution, the relative difference of 1.5% should be or less.

4.4 Determination of the mass fraction of deltamethrin

4.4.1 Method summary

Sample dissolved in mobile phase, isooctane dioxane as the mobile phase, used as a filler ZorbaxRX-Si1 stainless steel column and purple Outer detector (254nm), deltamethrin sample of normal phase high performance liquid chromatography, external standard.

4.4.2 Reagents and solutions

Iso-octane;

Dioxane;

Deltamethrin Sample. deltamethrin known mass fraction, w>=99.0%.

4.4.3 Instruments

HPLC. a variable wavelength UV detector;

Chromatographic data processor;

Column. 250mm × 4.6mm (id) stainless steel column, built ZorbaxRX-Si1,5µm filler;

Filter. membrane pore size of about 0.45 m;

Microsyringe. 50µL;

Quantitative sampling tube. 10µL;

Ultrasonic cleaning.

4.4.4 HPLC operating conditions

Mobile phase. [Psi] (isooctane. dioxane) = 90.10, by membrane filtration, and degassing;

Flow rate. 1.0mL/min;

Column temperature. room temperature;

Detection wavelength. 254nm;

Injection volume. 10µL;

Retention time. deltamethrin about 5.4min.

Are typical operating parameters of the above, according to the characteristics of different instruments, for a given operating parameters appropriately adjusted to obtain the best result.

Deltamethrin typical normal phase HPLC is shown in Figure 1.

1 --- deltamethrin;

2 --- solvent.

Normal phase HPLC Deltamethrin 1 of FIG.

4.4.5 Determination Step

4.4.5.1 Preparation of standard solution

Sample Weigh 0.05 g of deltamethrin (accurate to 0.0002g), was placed in a 50mL volumetric flask, add the mobile phase is shaken to dissolve, stream the mobile phase was diluted to the mark.

4.4.5.2 Preparation of sample solution

Weigh 0.05g of deltamethrin-containing sample (accurate to 0.0002g), was placed in a 50mL volumetric flask, dilute to the mark with the mobile phase, Shake well.

4.4.5.3 Determination

Under the above operating conditions, after the instrument is stable, the number of consecutive doses of the standard solution is injected until the peak area of the adjacent two pins is relatively deltamethrin After less than 1.2% of, measured according to the standard solution, sample solution, the sample solution, the order of standard solution.

4.4.6 Computing

The two needle and the sample solution was measured before and after the two doses of the standard sample solution and peak areas were averaged deltamethrin. Sample Deltamethrin Permethrin mass fraction calculated according to formula (1), the concentration of deltamethrin according to formula (2).

A2 · m1 · w

A1 · m2

rho1 =

A2 · m1 · rho · w × 10 A1 · m2 (2) where.

W1 --- deltamethrin sample content, expressed in%;

A2 --- sample solution, deltamethrin average peak area;

M1 --- Sample mass in grams (G);

W --- Sample mass fraction deltamethrin, expressed in%;

A1 --- the standard solution, the average peak area deltamethrin;

--- M2 mass of sample, grams (G);

rho] 1 --- deltamethrin sample concentration in grams per liter (g/L);

When the density of the sample rho --- 20 °C, in units of grams per milliliter (g/mL) (according to GB/T 4472-1984 of "densitometer method" Determination).

4.4.7 Allows poor

Deltamethrin relatively poor mass fraction (mass concentration) of the two parallel measurement result should be less than 4%, measured as the arithmetic mean Given result.

4.5 Determination of moisture content

According to GB/T 1600 in the "Karl Fischer method".

4.6 PH value measured

Carried out in GB/T 1601.

4.7 Emulsion stability test

Standard hard water sample was diluted 200-fold, tested in accordance with GB/T 1603, no floating oil (paste) in a measuring cylinder, and precipitation of heavy oil qualified.

4.8 Low temperature stability test

According to GB/T 19137 of "emulsions and a homogeneous liquid formulation" for the volume of the bottom of the educts 0.3mL centrifuge tube does not exceed qualified.

Thermal storage stability test 4.9 According to GB/T 19136 of "liquid formulation" performed. After the heat storage, deltamethrin content should be greater than the measured mass deltamethrin Prestorage Fraction of 97%, the emulsion stability should still meet the standards.

4.10 Product inspection and acceptance

Shall comply with the provisions of GB/T 1604's.

5.1 Marking, labeling, packaging

Deltamethrin EC mark, labeling and packaging should comply with the provisions of GB 4838; Deltamethrin large polyurethane packaging pail, Barrel net weight of not more than 200kg. Deltamethrin small package polyurethane bottle, net weight 100g (mL), 200g (ML), 250g (mL), 500g (mL); with outer plastic box or corrugated boxes, each box net content should not exceed 15kg; according to user Seeking agreement or order take other forms of packaging, subject to the provisions of GB 4838.

5.2 Storage

Deltamethrin package airiness, dry place; storage and transportation, prevent moisture and sunlight, no food, seeds and feed Feed mix, to avoid contact with the skin, eyes, mouth and nose to prevent inhalation.

5.3 Security

Deltamethrin is moderately toxic pyrethroid insecticides, are in contact with or inhalation of toxic, potentially fatal ingestion, contact with the eye may cause Pain, skin allergies. FDA should wear protective equipment, wash with soap after application. This product is no specific antidote, mainly thoroughly cleaned in addition to poisons and symptomatic treatment.

5.4 Warranty Period

Under the provisions of storage and transportation conditions, deltamethrin EC guarantee period, counting from the date of manufacture 2 years.

Appendix A

(Informative)

Deltamethrin other names, structural formulas and physicochemical parameters of the basic Other names, structural formulas and physicochemical parameters of the product basic active ingredient deltamethrin follows.

ISO common name. deltamethrin CIPAC Numeric Code. 333 Chemical name. (S) -alpha- cyano-3-phenoxybenzyl (1R, 3R) -3- (2,2- dibromo-vinyl) -2,2-dimethyl-cyclopropane carboxylate Structure.

Empirical formula. C22H19Br2NO3 Molecular weight. 505.2 Biological activity. Insecticides Melting point. 98 °C ~ 101 °C Vapor pressure (25 °C). 2.0 × 10-6Pa Solubility (20 °C, g/L). water