GBZ 5-2016Diagnosis of occupational fluorine and inorganic compound poisoning (English PDF)
职业性氟及其无机化合物中毒的诊断
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Issued by
National Health and Family Planning Commission
Level / Type
National · Mandatory
Issue date
January 18, 2016
Implementation date
July 1, 2016
Scope
GBZ 5-2016 is the English-translated version of 职业性氟及其无机化合物中毒的诊断.
GBZ 5-2016 — This standard specifies the principles for the diagnosis and treatment of occupational fluorine and its inorganic compound poisoning. This standard applies to the diagnosis and treatment of occupational fluorine and its inorganic compound poisoning.
This standard does not apply to the diagnosis and treatment of acute organofluorine poisoning and endemic fluorosis.
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Document preview — GBZ 5-2016
National Standard of the People's Republic of China
- ICS
- 13.100
- Classification
- C 60
- Replacing
- GBZ 5-2002
Issued by: National Health and Family Planning Commission
Contents
- Foreword
- 1 Scope
- 2 Normative references
- 3 Diagnostic principles
- 3.1 Acute poisoning
- 3.2 Chronic poisoning
- 4 Contact reaction
- 5 Diagnostic rating
- 5.1 Acute poisoning
- 5.2 Chronic poisoning
- 6 Processing principles
- 6.1 Principles of treatment
- 6.2 Other treatment
- 7 Instructions for the correct use of this standard
Foreword
This standard is formulated in accordance with the Law of the People's Republic Chapter 6 of this standard is recommended and the rest are mandatory.
This standard was drafted in accordance with the rules given in GB/T 1.1-2009.
This standard replaces GBZ 5-2002 "Diagnostic Standard for Industrial Fluorosis"; compared with GBZ 5-2002, the main technical changes are as follows.
--- The standard name was changed from "Diagnostic Standard for Industrial Fluorosis" to "Diagnosis of Occupational Fluoride and Its Inorganic Compound Poisoning";
--- Amend the "Diagnostic Principles of Industrial Fluorosis" to "Diagnostic Principles of Chronic Poisoning";
--- Amend the "segmentation of bone X-ray changes" to "chronological diagnosis of chronic poisoning";
--- Deleted the observation object;
--- Increased the diagnosis and treatment of acute fluoride and its inorganic compound poisoning.
1 Scope
This standard specifies the principles for the diagnosis and treatment of occupational fluorine and its inorganic compound poisoning.
This standard applies to the diagnosis and treatment of occupational fluorine and its inorganic compound poisoning.
This standard does not apply to the diagnosis and treatment of acute organofluorine poisoning and endemic fluorosis.
2 Normative references
The following documents are indispensable for the application of this document. For dated references, only the dated version applies to this article.
Pieces. For undated references, the latest edition (including all amendments) applies to this document.
GB/T 16180 Labor ability appraisal employee injury and occupational disease disability level GBZ 51 diagnostic criteria for occupational chemical skin burns GBZ 73 Occupational acute chemical toxicity diagnostic criteria for respiratory diseases GBZ 74 Diagnostic criteria for occupational acute chemical toxicity heart disease GBZ/T 228 diagnostic criteria for sequelae of occupational acute chemical poisoning WS/T 30 method for determination of ion selective electrode in urine WS/T 212 Determination of fluoride in serum - Ion selective electrode method
3 Diagnostic principles
3.1 Acute poisoning
According to the occupational history of exposure to higher concentrations of fluoride and its inorganic compounds in the short term, acute respiratory damage and symptomatic hypocalcemia are the main clinical manifestations, combined with laboratory blood (urine) fluoride and blood calcium and other test results, refer to the job site occupational health information, exclude other reasons After a similar disease, a comprehensive analysis can be diagnosed.
3.2 Chronic poisoning
According to the occupational history of close contact with fluorine and its inorganic compounds for 5 years and above, the clinical manifestations based on skeletal damage, combined with experiments the results of blood (urine) fluoride test, refer to occupational health information on the job site, and exclude other diseases caused by other causes, comprehensive analysis diagnosis.
4 Contact reaction
After short-term exposure to a large amount of fluorine and its inorganic compounds, one of the following manifestations occurred and was significantly reduced or disappeared within 72 hours of disengagement.
a) eye pain, tearing, photophobia, cough, sore throat, chest tightness and dizziness, fatigue, palpitations and other symptoms;
b) Blood calcium is reduced but has no clinical manifestations.
5 Diagnostic rating
5.1 Acute poisoning
5.1.1 Mild poisoning
Short-term exposure to higher concentrations of inorganic fluoride, dizziness, fatigue, cough, sore throat, palpitations, chest tightness, nausea, vomiting and other symptoms and blood (urine) fluoride Increased and has one of the following performances.
a) acute tracheal-bronchitis (see GBZ 73);
b) 1 degree to 2 degrees of laryngeal edema (see GBZ 73);
c) ECG shows prolonged QT interval or abnormal ST-T changes;
d) Paroxysmal supraventricular tachycardia or single-source ventricular premature contraction (see GBZ 74).
5.1.2 Moderate poisoning
Based on 5.1.1, it has one of the following performances.
a) acute bronchial pneumonia or interstitial pulmonary edema (see GBZ 73);
b) 3 degree laryngeal edema (see GBZ 73);
c) paroxysmal ventricular tachycardia or multi-source ventricular premature contraction (see GBZ 74);
d) Repeated convulsions.
5.1.3 Severe poisoning
Based on 5.1.2, it has one of the following performances.
a) alveolar pulmonary edema (see GBZ 73);
b) acute respiratory distress syndrome (see GBZ 73);
c) 4 degrees of laryngeal edema or asphyxia (see GBZ 73);
d) hypocalcemia crisis (ventricular tachycardia, ventricular fibrillation and epileptic seizures);
e) Sudden death.
5.2 Chronic poisoning
5.2.1 Mild poisoning
Long-term close contact with fluorine and its inorganic compounds, and one of the following manifestations.
a) The trunk bone (pelvis and lumbar vertebrae) are mainly changed; the bone density is increased; the trabecular bone is thickened and thickened, and it is "gauze-like";
b) There is a clear calcification or ossification of the periorbital bone (osteophyseal, interosseous membrane) of the ulna, ulna or iliac crest.
5.2.2 Moderate poisoning
The bone density of the trunk was significantly increased; the trabecular bone was significantly thickened, showing a "sack pattern"; accompanied by a defined change in the periosteum and periosteum of the long bone.
5.2.3 Severe poisoning
Most of the bones in the body are involved; the bone density is significantly increased, the trabecular bone is blurred, and it is "marble-like"; the long bone cortex is thickened and the medullary cavity is changed.
Narrow; periosteal changes are more obvious, bone bridges can form between the vertebral bodies.
6 Processing principles
6.1 Principles of treatment
6.1.1 Acute poisoning
6.1.1.1 Keep the airway open and perform a tracheotomy if necessary.
6.1.1.2 Dynamic monitoring of blood fluoride, blood calcium, myocardial enzymes and electrocardiogram.
6.1.1.3 Early intravenous supplementation of a sufficient amount of calcium.
6.1.1.4 Other symptomatic and supportive treatments, protection of cardiopulmonary and other multi-organ function.
6.1.1.5 Burning skin should be treated with wounds in the early stage (see GBZ 51).
a) The wound is wet or soaked with calcium and magnesium suspension and sodium bicarbonate solution;
b) Deep burn wounds, early implementation of cutting (shaving) sputum surgery.
6.1.2 Chronic poisoning
Strengthen nutrition, supplement vitamin D and other preparations, and also appropriate calcium supplementation, and give symptomatic treatment and strengthen bone function exercise.
6.2 Other treatment
If there are sequelae, it can be carried out in accordance with GBZ/T 228. If you need a labor ability appraisal, deal with it according to GB/T 16180.
7 Instructions for the correct use of this standard
See Appendix A.
Appendix A
(informative appendix) Instructions for the correct use of this standard A. 1 Acute fluorosis A. 1.1 The most common fluorides causing occupational acute fluoride and its inorganic compounds poisoning are hydrogen fluoride and hydrofluoric acid, followed by elemental fluorine, three Boron fluoride, silicon tetrafluoride, fluorosilicic acid, oxygen difluoride, nitrogen trifluoride, sulfur pentafluoride, sulfur hexafluoride, sulfur hexafluoride and uranium hexafluoride.
A. 1.2 Fluoride mainly invades the human body through the skin mucosa and respiratory tract, leading to poisoning. The clinical manifestations of fluorosis caused by different invasive pathways are endless.
the same.
a) Inhalation poisoning in the respiratory tract alone. Most of them are caused by inhalation of hydrogen fluoride or hydrofluoric acid mist, and the clinical manifestations are acute respiratory damage.
Mainly harmful. Immediately after inhalation, there are irritation such as cough, sore throat, and shortness of breath. Severe cases have a lot of foam, and both lungs can smell wet.
Arpeggio, chest X-ray images of bronchitis, chemical pneumonia or pulmonary edema, severe acute respiratory distress Combined.
b) Simple burns the skin to absorb poisoning. Mostly caused by hydrofluoric acid burns, clinical manifestations of acute cardiovascular system caused by hypocalcemia Damage is dominant. Some may have repeated convulsions. Mild symptoms can increase myocardial enzyme activity index or muscle calcium egg within 48 hours after injury White positive. Electrocardiogram mainly shows QT interval prolongation and ST-T abnormal changes; severe cytotoxicity due to fluoride ion and hypocalcemia, electrocardiogram showed T wave low level and conduction block, frequent premature beats, severe ventricular tachycardia, ventricular fibrillation and other arrhythmias, or epilepsy-like convulsions, or even sudden death.
c) Burning skin absorption and inhalation poisoning. Mostly found in hydrofluoric acid burn concentration > 40% and there is a burn in the face and neck. Illness the degree is often severe, and the rate of sudden death is high. Even a small area ( Appendix B (normative appendix) Bone X-ray film requirements B. 1 Using an X-ray diagnostic machine with a frequency of.200 mA or more, the focus size is not more than 2.0 mm × 2.0 mm, preferably a rotating anode bulb.
B. 2 Photographing parts. The basic requirements are pelvic anteroposterior, one side iliac crest, ulnar anteroposterior and ipsilateral iliac crest, tibia positive and lateral radiographs;
Department and lumbar vertebrae.
B. 3 The requirements for the conditions of the investment are shown in Table B. 1.
Table B. 1 Requirements for investment conditions
Film location target distance cm Exposure mAs Tube voltage kV filter Pelvis 100 100~150 Thickness (cm)×2+(30~40) + , ulna 100 25 ~ 30 thickness (cm) × 2+ (30 ~ 40) -, bone 100 30 ~ 40 thickness (cm) × 2+ (30 ~ 40) -Lumbar spine 100 100 ~ 150 thickness (cm) × 2+ (30 ~ 40) + Chest 150 20 ~ 25 thickness (cm) × 2+ (30 ~ 40) -Note. X-ray film is best used with a blue base.
B. 4 Photographic quality requirements. The position of the film is accurate, the contrast is good, the direct exposure area is black, the soft tissue is gray, the layers are distinct, the cortex and the trabecular bones are clearly displayed.
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